


2019-01-18
ION HANCU
ION HANCU

2019-01-29
MARIA MAFFEI
MARIA MAFFEI

2019-02-13
BORIS BOURDONCLE
BORIS BOURDONCLE

2019-02-15
JORDI MORALES DALMAU
JORDI MORALES DALMAU

2019-02-22
FRANCESCO RICCI
FRANCESCO RICCI

2019-03-06
CLARA GREGORI
CLARA GREGORI

2019-03-26
ALEXIA SALAVRAKOS
ALEXIA SALAVRAKOS

2019-04-12
SENAIDA HERNANDEZ SANTANA
SENAIDA HERNANDEZ SANTANA

2019-04-15
DAVID RAVENTÓS RIBERA
DAVID RAVENTÓS RIBERA

2019-04-16
PETER SCHMIDT
PETER SCHMIDT

2019-04-29
CALLUM O’DONNELL
CALLUM O’DONNELL

2019-05-02
LUCIANA VIDAS
LUCIANA VIDAS

2019-05-03
HANYU YE
HANYU YE

2019-05-10
TANJA DRAGOJEVIC
TANJA DRAGOJEVIC

2019-05-17
FLAVIO BACCARI
FLAVIO BACCARI

2019-06-04
MARTINA GIOVANNELLA
MARTINA GIOVANNELLA

2019-07-02
OZLEM YAVAS
OZLEM YAVAS

2019-07-03
ALESSANDRO SERI
ALESSANDRO SERI

2019-07-11
RENWEN YU
RENWEN YU

2019-09-06
ALEXANDER BLOCK
ALEXANDER BLOCK

2019-10-04
MARCO PAGLIAZZI
MARCO PAGLIAZZI

2019-10-07
RINU MANIYARA
RINU MANIYARA

2019-10-15
ALEJANDRO POZAS-KERSTJENS
ALEJANDRO POZAS-KERSTJENS
Correlates of Cerebral Vasoreactivity Measured by Non-Invasive Diffuse Optical Measurements as Biomarkers of Brain Injury Risk


CLARA GREGORI
March 6th, 2019
CLARA GREGORI
Medical Optics
ICFO-The Institute of Photonic Sciences
I have used and developed a practical new platform in the clinics for the noninvasive estimation of cerebral hemodynamics. The platform combines two diffuse optical techniques: near-infrared spectroscopy and diffuse correlation spectroscopy.
To study patients at a high risk of cerebrovascular accidents, and those who have recently suffered an ischemic stroke, several protocols were devised and carried out. This set of multi-disciplinary studies was performed in close collaboration with the Stroke Unit and the Sleep Unit at Hospital de la Santa Creu i Sant Pau (Barcelona, Spain) with the ultimate goal to identify new biomarkers for the assessment of cerebral autoregulation and cerebral vasoreactivity, and, ultimately, cerebral well-being.
The bulk of the studies on these patients focused on the investigation of microvascular cerebral physiology in response to a non-invasive and benign challenge, without the need of patient collaboration nor any additional equipment. This challenge involved an alteration of the patient head-of-bed positioning. Interestingly, the head-of-bed challenge with the measurement of microvascular cerebral blood ow has been shown as a potential protocol to tell us about the status of cerebral autoregulation in these patients. This in turn was shown to track impairments over time, and the patients’ response to treatments, and to predict long-term outcome.
Overall, this thesis pushes the limits of the clinical translation of hybrid diffuse optics, paving the way for new clinical applications at the point-of-care and in the neurocritical care.
Wednesday, March 6, 11:00. ICFO’s Auditorium
Thesis Advisor: Prof Dr Turgut Durduran
ICFO-The Institute of Photonic Sciences
I have used and developed a practical new platform in the clinics for the noninvasive estimation of cerebral hemodynamics. The platform combines two diffuse optical techniques: near-infrared spectroscopy and diffuse correlation spectroscopy.
To study patients at a high risk of cerebrovascular accidents, and those who have recently suffered an ischemic stroke, several protocols were devised and carried out. This set of multi-disciplinary studies was performed in close collaboration with the Stroke Unit and the Sleep Unit at Hospital de la Santa Creu i Sant Pau (Barcelona, Spain) with the ultimate goal to identify new biomarkers for the assessment of cerebral autoregulation and cerebral vasoreactivity, and, ultimately, cerebral well-being.
The bulk of the studies on these patients focused on the investigation of microvascular cerebral physiology in response to a non-invasive and benign challenge, without the need of patient collaboration nor any additional equipment. This challenge involved an alteration of the patient head-of-bed positioning. Interestingly, the head-of-bed challenge with the measurement of microvascular cerebral blood ow has been shown as a potential protocol to tell us about the status of cerebral autoregulation in these patients. This in turn was shown to track impairments over time, and the patients’ response to treatments, and to predict long-term outcome.
Overall, this thesis pushes the limits of the clinical translation of hybrid diffuse optics, paving the way for new clinical applications at the point-of-care and in the neurocritical care.
Wednesday, March 6, 11:00. ICFO’s Auditorium
Thesis Advisor: Prof Dr Turgut Durduran