The Lämmermann investigates the mechanisms that shape single cell and population dynamics of immune cells in the complexity of inflamed and infected tissues. By using a broad range of microscopy and imaging techniques, we explore the strategies that immune cells have evolved to move individually or in concert with other cells in order to achieve together an optimal immune response. In particular, we are interested in how immune cells coordinate and integrate fundamental cell biological processes (directional sensing, cytoskeletal regulation, cell adhesion, cell migration, phagocytosis, cell death, cell survival, cell-cell communication) that together shape the dynamics of an immune response in complex tissue environments. The talk will focus on the swarming behavior of neutrophils and the cytoskeletal requirements for immune cell movement and positioning in tissues.