Dynamic nanolandscape of immune receptors
Exploit state-of-the-art optical nanoscopy to unravel the nanolandscape of cells of the immune system.
Our aim is to exploit state-of-the-art optical nanoscopy to unravel the nanolandscape of cells of the immune system and get dynamic information of the cell surface organization of cellular receptors and subsequent signalling pathways at the nanometer level. In particularly in the immune system, which defends our body against pathogens, recognition and elimination of nanometer-sized pathogens is regulated through complex cell signaling and cell communication to ensure a swift and effective protective response. Understanding how these cell surface processes are orchestrated at the molecular level on living cells is at the core of this project.
For more information see the BioNano@ICFO website.
Funding:
HFSP advanced grant; MINECO Severo Ochoa, Fundacio Privada CELLEX Barcelona, MINECO-FIS2014-56107-R.
Collaborators:
- Dr. Alessandra Cambi -NCMLS, Nijmegen (NL)
- Prof. Enzo Curundolo - Weatherall Institute of Molecular Medicine, Oxford University (UK)
- Prof. Javier Martinez-Picado - IrsiCaixa, Badalona (ES)
- Dr. Daniel Benitez-Ribas - Hospital Clinic Barcelona, (ES)