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SLN - Team Wieser

Dr. Stefan Wieser

    Activities:

Our team works at the interface of physics and biology. We are developing live cell super-resolution imaging techniques for 3D imaging of whole cell dynamics. We mainly focus on immune cells with the aim to study the intrinsic coupling between leucocyte migration, cell polarization and antigen presentation. To gain a mechanistic understanding of these processes we apply advanced imaging techniques - with focus on SIM - and data analysis tools that allow for integrating molecular dynamics with large-scale cell behavior. The ultimate goal is to develop mathematical models with predictive capacity from the molecular scale to global cell behavior and immune cell function.

    Collaborations:
      Research Topics:
    • Lattice Light Sheet Microscopy
    • High NA-TIRF Structured Illumination Microscopy
    • 2D/3D live cell single molecule imaging
    • Advanced biomimetic interfaces
    • Quantitative Data Analysis Tools and Monte Carlo Simulations
    • Immune cell migration
    • Temperature control of immune cell responses

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SLN - Team Wieser

Dr. Stefan Wieser

    Former Group Members
  • Johannes Ziegler, Research engineer

SLN - Team Wieser

Dr. Stefan Wieser

    Talks
  • How do cells sense physical forces? Cellular mechanosensing and motility in biomimetic 3D environments V. Venturini, F. Pezzano, M. Marro, P., Loza-Álvarez, M. A. de Castro, S. Wieser, V. Ruprecht Joint 12th EBSA European Biophysics Congress / 10th IUPAP International Conference on Biological Physics (ICBP), Madrid, Spain, July 2019
  • Mechanosensitive actomyosin network dynamics and migration plasticity in 3D environments V. Venturini, F. Pezzano, S. Wieser. V. Ruprescht Joint 12th EBSA European Biophysics Congress / 10th IUPAP International Conference on Biological Physics (ICBP), Madrid, Spain, July 2019
  • SIMPLE: Structured illumination localization microscopy S. Wieser, L. Reymond, J. Ziegler, V. Ruprecht, V. Ruprecht Joint 12th EBSA European Biophysics Congress / 10th IUPAP International Conference on Biological Physics (ICBP), Madrid, Spain, July 2019
    Masters Theses
  • High temperature triggers immediate morphological changes and a sustained increased efficiency in neutrophil migration I. Company-Garrido
  • Towards a size estimation of nanostructrues using structured illumination microscopy C. Kumar
    PhD Theses
  • Development and application of localization-based microscopy methods to study the structure and dynamics of chromatin through the process of cellular differentiation P. Gómez García

SLN - Team Wieser

Dr. Stefan Wieser